Cell Lines and Cell Cultures
ATCC HCT116-SLC35B3-KO-c11; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC35B3-KO-c11 cell line contains a -5 deletion in SLC35B3 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
ATCC Quantitative Genomic DNA from; Enterococcus hirae; Strain: FDA M19
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Human rhinovirus 17; RNA; Strain: 33342
Genomic RNA isolated from H1 HeLa cells (ATCC CRL-1958) infected with Human rhinovirus 17 strain 33342 (ATCC VR-1663). This product was prepared using methods known to inactivate viruses. It is suitable for use in RT-PCR or other RNA-based procedures. The source organism and host cells are also available through the ATCC catalog.
ATCC Merck Pneumococcal polysaccharide powder Type 3 (d3) 10mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae.Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
ATCC Scedosporium apiospermum; SC2
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
ATCC Bacillus atrophaeus
Bacillus atrophaeus strain NRS 1221A is a whole-genome sequenced bacterial strain with applications as a test microorganism for sterilization and sterility assurance.
Eurofins Discoverx Ready-to-Assay P2Y4 Purinergic Receptor Frozen Cells, 2 Vials of Cells. (HTS211RTA)
The Ready-to-Assay P2Y4 Purinergic Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. ATP, UTP) based activation of P2RY4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses P2RY4, a naturally Gq coupled GPCR. Upon activation of P2RY4, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen GPR109A Nicotinic Acid Receptor Stable Cell Line, 2 vials. (HTS201C)
The ChemiScreen GPR109A Nicotinic Acid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. nicotinic acid) based activation of HCAR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HCAR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of HCAR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen S1P5 Lysophospholipid Receptor Stable Cell Line, 2 vials. (HTS193C)
The ChemiScreen S1P5 Lysophospholipid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. S1P) based activation of S1PR5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses S1PR5 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of S1PR5, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Rotavirus A; Strain: WA (TC-adapted)
Rotavirus A strain Wa is propagated in MA-104 Clone 1 cells (ATCC CRL-2378.1). This strain was isolated from the diarrhea stool from patient positive for rotavirus and was deposited by National Institute of Allergy and Infectious Disease. It has applications in efficacy testing, virucide testing, and enteric research.
ATCC Thermoanaerobacterium; thermosaccharolyticum; Strain NCA 3814
Thermoanaerobacterium thermosaccharolyticum strain NCA 3814 is a thermophilic anaerobe. This bacterial type strain is whole-genome sequenced and can be propagated on PRAS-PYG with tween 80.
As One International Inc Red Fluorescent SH-SY5Y Cell Line, 3 x 10^6 cells/vial
Red Fluorescent SH-SY5Y Cell Line, 3 x 10^6 cells/vial
Biochain Institute Inc Multiple Species Paraffin Tissue Array - Brain, 5 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.